International Conference on
Pharmaceutics and Novel Drug Delivery System

Drug safety also known as the Pharmacovigilance is the study relating to the collection, detection, monitoring, assessment with the prevention of the adverse effects of the pharmaceutical products. They play a potential key role in all of the pharmaceutical industry for the novel drug development and testing of various new medications. The main goal of Pharmacovigilance is to reduce the adverse drug reactions by the drug and ensure safe use of medication to maximize the benefits of medical product.

• Track 2-1Pharmacovigilance
• Track 2-2Adverse drug reactions
• Track 2-3Risk Management
• Track 2-4Pharmacoenvironmentology
• Track2-5Herbal medicines

The applied branch of Microbiology is the Pharmaceutical Microbiology with often deals with the use of microorganisms in the manufacture of Pharmaceutics. In the 21^st century there have been many progresses in the pharmaceutical microbiology with the rapid microbiological methods, conventional testing methods and the introduction of human microbiome studies. The Human Microbiome Projects have also hit around the globe with various developments in the Pharmaceutical Microbiology and Biotechnology. Growth of Biotechnology world also favours the Pharmaceutics and novel drug development systems studies.

• Track 3-1Pharmaceutical Microbiology
• Track 3-2Biopharmaceutics and drug disposition
• Track 3-3Pharmaceutical technology
• Track3-4 Pharmaceutical Biotechnology
• Track3-5Human Microbiome Project

Novel drug delivery may be a method of delivering medication to a patient in a very manner that increases the concentration of the medication in some parts of the body relative to others. this suggests of delivery is basically founded on nanomedicine, which plans to use nanoparticle-mediated drug delivery so as to combat the downfalls of conventional drug delivery. Such that these nanoparticles are loaded with effective drugs and targeted to specific parts of the body wherein specific to diseased tissue and thereby avoiding interaction with healthy tissue. The goal of targeted drug delivery systems is to target, prolong, and localize to have a protected drug interaction with the diseased tissue. The traditional drug delivery system is that the absorption of the drug across a biological membrane, whereas the targeted release system releases the drug in a very dosage form. the benefits to the targeted release system is that the reduction within the frequency of the dosages taken by the patient, having a more uniform effect of the drug, reduction of side-effects of the drugs and reduced fluctuation in circulating drug levels. The disadvantage of the system is high cost, which makes productivity tougher and also the reduced ability to regulate the dosages.

• Track 4-1Drug delivery carriers
• Track 4-2Nano based drug delivery system
• Track 4-3Lipid Nanoparticle Drug Delivery System
• Track 4-4Liposomes -ocular drug delivery
• Track 4-5Hydrogel based drug delivery systems
• Track 4-6Electrospun and Electrospray

Drug Design is often remarked as rational drug design or just rational design, the inventive process of finding new medications supported the knowledge of a biological target. The drug is most ordinarily an organic small molecule that activates or inhibits the function of a biomolecule like a protein, which successively ends up in a therapeutic benefit to the patient. Drug design involves the planning of substances or the molecules which are complementary in shape and charge to the biomolecule target with which they interact and thus will bind to the targeted molecule. Within the most simple sense drug design habitually but not necessarily relies on computer modelling techniques. This sort of modelling is usually remarked as computer-aided drug design. Finally, drug design that relies on the knowledge of the three-dimensional structure of the biomolecule target is thought as structure-based drug design. As well as to pharmaceutics, biopharmaceuticals and particularly therapeutic antibodies are an increasingly important class of medicine for the drug delivery system; computational methods for improving the selectivity, affinity and stability of this protein-based therapeutics have also been developed.

• Track 5-1Drug targeting strategies
• Track 5-2Factors influencing drug targeting
• Track 5-3Advances in drug targeting components
• Track 5-4Recent approaches to drug targeting
• Track 5-5Computer aided drug design
• Track5-6Rational drug design

Biopharmaceutical products are molecules that are the components of biological systems that are used in the treatment of human and animal health and disease. Formulation development of biopharmaceutical protein therapeutics. Production of biopharmaceutical involves many different complex steps which synthesis is purification, formulation, final dosage preparation. Applications of biopharmaceuticals are agonist and antagonist of important receptors and enzymes, vaccines. The combination of biological molecules like antibodies with cytoxic compounds and agents, such as antibody drug used in cancer therapies

•  Track 6-1Biopharmaceutics
•  Track 6-2Pharmaceutical technology and drug disposition
•  Track 6-3Active Pharmaceutical Ingredients
•  Track 6-4Biopharmaceutical Support in Formulation
•  Track 6-5Biopharmaceutical Microbiology and Biotechnology

 Pharmacotherapy are often characterized because the treatment and counteractive action of ailment and ailment by methods for medications of the synthetic or organic root. It positions among essential techniques for therapeutic treatment, together with surgery, physical therapy, radiation, and psychotherapy. Although it's practically difficult to appraise the right degree of the effect of pharmacotherapy on human well-being, there are often almost certain that pharmacotherapy, alongside enhanced sanitation, better-eating regimen, and better lodging, has improved individuals. Phenomenal advancements in genomics and atomic science today offer a many new medication targets. The utilization of present-day concoction manufactured strategies empowers the blend of the many medication hopefuls in shorter circumstances than at the other time.

• Track 7-1Biopharmaceutics and drug disposition
• Track 7-2Pharmaceutical technology
• Track 7-3Pharmaceutical Microbiology & Biotechnology

Drug delivery is that the action of administering a drugs into the body for a therapeutic effect through various routes. Drug delivery technology modifies drug release profiles, pharmacokinetic parameters to boost product efficacy in addition as patient convenience. Conventional routes cannot deliver compounds like antibodies, proteins, gene, vaccine and gene based drugs because these routes are vulnerable to enzymatic degradation or can't be absorbed into the circulation efficiently thanks to large molecular size and charge issues. Technologies include controlled sustained, needle-free devices, controlled transdermal delivery technology along with penetration matrix technology for non-invasive delivery. Most of the innovative technologies for effective drug delivery are developed that features nanotechnology, implants, cell and peptide, micro fabrication, chemical modification and encapsulation. Biotechnology advances are resulting in develop medications to focus on diseases more effectively and precisely

• Track 8-1Intravenous
• Track 8-2Oral
• Track 8-3Intramuscular
• Track 8-4Subcutaneous
• Track 8-5Intrathecal

Vaccines are substances that induce an immunologically mediated resistance to a disease but not necessarily an infection. They are generally composed of killed or attenuated organisms or sub units of organisms or DNA encoding antigenic proteins of pathogens. Delivery of antigens from oil-based adjuvants like Freunds adjuvant result in a discount within the number of doses of vaccine to be administered but thanks to toxicity concerns like inductions of granulomas at the injection site, such adjuvants don't seem to be widely used.FDA approved adjuvants for human uses are hydrated oxide and aluminium phosphate within the variety of alum. So there is a need for safer and potent adjuvants resulted within the formulations of antigen into delivery systems that administer antigen in particulate form instead of solution form

• Track 9-1Edible vaccines
• Track 9-2DNA vaccines
• Track 9-3Needle-free delivery
• Track 9-4Polymeric nanoparticle delivery system
• Track 9-5Micellar delivery system
• Track9-6Mucosal delivery

The goal of drug delivery systems is to deliver medications to specific target parts of the body through a medium which can control the therapy’s administration. To understand this goal, researchers are switching to advances within the worlds of micro and nanotechnology. The recent advances within the peptide, protein drug delivery systems are PEGylation and Depo-foam technology. Cell-penetrating peptides (CPPs) act as cargo carriers which constitute current medical research. CPPs to manoeuvre hydrophilic macromolecules into cells, thus, assist to execute biological functions. CPPs don't destroy the integrity of the cell membranes in order that they're considered more efficient and provide new avenues for research and applications in life sciences.

• Track 10-1Nanotechnology
• Track 10-2Digital Pharma
• Track 10-3Polymers in drug delivery system
• Track 10-4Artificial Intelligence in Pharma
• Track 10-5RAFT Technology

The evolution of protein and peptide therapeutic market has developed significantly in the past decades with the advancement of peptide and protein drug delivery system. Although oral delivery is preferred, most are currently delivered intravenously or subcutaneously thanks to degradation and limited absorption within the alimentary canal. Due to rapid progress in biotechnology, as well as gene technology, the industry can produce many potential therapeutic peptides and proteins in commercial quantities. Endogenous proteins and peptides play a crucial role within the regulation and integration of life processes and act with high specificity and potency. Peptides and proteins have great potential as therapeutics. Currently, the marketplace for peptide and protein drugs is estimated to be greater than US$40 billion/year, or 10% of the pharmaceutical market. This market is growing much faster than that of small molecules and will make up an even larger proportion of the market in the future.

• Track 11-1Peptide Vector for Biologics Brain Delivery
• Track 11-2Protein & peptide therapeutics
• Track 11-3Cell-penetrating and cell-targeting
• Track 11-4Oxidation and deduction

Nano drug delivery systems such dendrimers, fullerene, Nano pores, Nanotubes, Nano shells, quantum dots, Nano vaccines, revolutionized drug delivery systems. Nanoparticles are generally 100 nm in dimension and incorporate different biodegradable materials like natural or synthetic polymers, lipids, or metals. Nanoparticles are haunted by cells more efficiently than larger micro-molecules. Nanoparticles have high expanse to volume ratio thus allowing many functional groups for attachment. The tiny size of nanoparticles allows them to accumulate at sites. Nanoparticles enhance the efficacy of the drugs and thereby minimize adverse reactions and also encourage the re-investigation of pharmaceutically sub-optimal but biologically active new molecules that were previously considered undeveloped and enable new classes innovations. Nanoparticles are employed in drug delivery to boost the uptake of poorly soluble drugs.

• Track 12-1Nano drugs, Nanomaterial & biopharmaceuticals
• Track 12-2Nanotechnology in industrial safety
• Track 12-3Nano mechanism of molecule
• Track 12-4Nanotechnology in cancer research & targeted drug delivery
• Track 12-5Bio nanotechnology & pharmaceutical engineering

Pharmacogenomics joins pharmacology and genomics to create successful, safe drugs and dosages that will be customized to a man's hereditary capacity. Pharmacogenomics utilize is right now very constrained, yet new methodologies are under examination in clinical trials. It plans to improve tolerant novel drug administration by blending drugs and modifying in light of hereditary varieties in sedate reaction

•  Track 13-1Pharmacogenomics Research
•  Track 13-2Real-time PCR solutions
•  Track 13-3Drug response
•  Track 13-4Biological marker
•  Track 13-5Pharmacogenetic Testing

Green pharmacy is one of the new approach where it's about the environment, social and economic aspects, that which deals with the environment issues on the pharmaceutical entity that deals with the resources and waste issues as an example during the synthesis of a product there would be several compounds which cannot degrade and causes harm to the environment to scale back such risk aspects are to be analysed. Another issue is that the people using pharmaceuticals like pharmacists, medical doctors and patients. How can they contribute to more efficient use of pharmaceuticals with less environmental burden and fewer risks for water?

• Track 14-1Sustainable chemistry
• Track 14-2Green Pharmacy
• Track 14-3Greener synthetic Pathway
• Track 14-4Green Pharmaceuticals
• Track 14-5Biodegrable substances

One of the largest challenges within the drug discovery and development for CNS disorders is to realize significant blood–brain barrier (BBB) penetration. Many drugs don't have high lipid solubility, low molecular size and charge to traverse BBB. The problems related to the blood–brain barrier are 1. The drug produced allows only a tiny low portion to undergo the barrier 2. Binding to other proteins within the body makes the drug ineffective or undergo the barrier thereupon adhered protein. The presence of enzymes within the brain might render the drug inactive. All of those problems must be addressed to deliver effective drugs to the brain. The developed strategies would enhance the ability of drug to cross the BBB by modifying the drug or by binding it to a vector for adsorption-mediated or receptor-mediated transcytosis.

• Track 15-1Blood Brain Barrier
• Track 15-2Drug Efflux
• Track 15-3CNS Drug Delivery
• Track 15-4Biodistribution and Targeting of BBB

Herbal formulation is defined as a mean dosage form consisting of one or more herbs in specified quantities to provide specific nutritional, cosmetic benefits and used to treat, diagnose, mitigate diseases of human beings. Herbal drugs/herbal formulations are finished labelled products that contain active ingredients such as aerial or underground parts of plant or combinations whether in the crude state or as plant preparations. Herbal preparations are available in different forms including fresh, dried, in tablets, or capsules, or bottled in liquid form. Very rare pharmaceutical companies are involved in drug discovery screening from natural sources which are the novel drug formulation techniques.

• Track 16-1Chemical Constituents of Herbal Medicine
• Track 16-2Benefits of Herbal Medicine
• Track 16-3New products based on biological resources
• Track 16-4Herbs used for various biological conditions
• Track 16-5Cupping Therapies

Needle-free drug delivery systems are novel ways to introduce various medicines to patients with disorders. Needle-free technologies are used for injecting powdered drugs into the skin. Needle free devices can take the shape of power sprays, edible products, inhalers, and skin patches. Transdermal patches are user-friendly, convenient, and painless offer improved patient compliance.

• Track 17-1Pharmaceutical business
• Track17-2Pharmaceutical research
• Track17-3Pharmacetical development
• Track 17-4Bio-Pharmaceutical research

The last session of the conference winds with the discussion of the clinical research and medical case reports in the Pharmaceutical industry along with the novel drug delivery system. This session enrich all of us with all the reports of clinical and medical research that offers an interesting publishing platform globally and aims to keep scientists, clinicians and medical practitioners, researchers, and students updated on the on-going research in the relevant area.

• Track 18-1Clinical research in Pharmaceutical industry
• Track 18-2Clinical reports
• Track 18-3Medical reports